Minimal Change Disease (MCD): Morphology

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Synonyms:

1. Lipoid necrosis
2. Foot process disease
3. Nil disease

Gross appearance:

1. Kidneys are of normal size and shape

Microscopic appearance:

1. Light microscopy: Normal glomeruli, Lipid in tubules
2. Electron microscopy: Podocyte foot process effacement, No deposits
3. Fluorescence microscopy: Negative (no complement/Ig deposits)